منابع مشابه
Regulatory Roles for Long ncRNA and mRNA
Recent advances in high-throughput sequencing technology have identified the transcription of a much larger portion of the genome than previously anticipated. Especially in the context of cancer it has become clear that aberrant transcription of both protein-coding and long non-coding RNAs (lncRNAs) are frequent events. The current dogma of RNA function describes mRNA to be responsible for the ...
متن کاملEvolutionary conservation and functional roles of ncRNA
Non-coding RNAs (ncRNAs) are a class of transcribed RNA molecules without protein-coding potential. They were regarded as transcriptional noise, or the byproduct of genetic information flow from DNA to protein for a long time. However, in recent years, a number of studies have shown that ncRNAs are pervasively transcribed, and most of them show evidence of evolutionary conservation, although le...
متن کاملDown with ncRNA! Long live fRNA and jRNA!
Noncoding RNA (ncRNA) and long noncoding RNA (lncRNA) are scientifically invalid terms because they define molecular entities according to properties they do not possess and functions they do not perform. Here, I suggest retiring these two terms. Instead, I suggest using an evolutionary classification of genomic function, in which every RNA molecule is classified as either"functional"or"junk' a...
متن کاملP7: The Roles of Long-Term Memory on the Organization of the Knowledge for Educators
Modern neuroscientific research help to solve the impotent challenge in curriculum design and teaching for enhancing students’ ability to organize information in a way that makes it efficient in response to an appropriate context such as problem solving and critical thinking via knowing about the mechanism of different type of memories especially long term memory. At first, we should to c...
متن کاملRegulatory and Biosafety Challenges for Vaccines
The global regulatory plan for vaccines provides a unique opportunity to develop safe and effective ones with assured quality. Methods used by regulators address challenges of new products and technologies and also increase understanding of benefits and risks of existing products. First, the laboratory-based regulatory sciences evolve correlates of immunity and safety; or improve the product ch...
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ژورنال
عنوان ژورنال: Cancers
سال: 2013
ISSN: 2072-6694
DOI: 10.3390/cancers5020462